Marie Bonaparte was a descendant of Napoleon Bonaparte's brother Lucien. Her parents were Roland Bonaparte and his wealthy wife Marie-Félix Blanc, who died a month after Marie's birth. She was born and raised at Saint-Cloud, near Paris, with few companions, and rarely saw her father, who spent most of his time on his work with the Geographical Society. In 1907, she married Prince George of Greece and Denmark, 13 years her senior, with whom she had two children. Princess Marie became interested in psychoanalysis, and after analysis with Sigmund Freud, she became a well-known analyst and writer herself. She and Freud were close and she translated his work into French. She used her wealth to put up the ransom that the Nazis required to allow Freud and his family to leave Vienna for London in 1938. She also helped at least 200 other Jewish families flee from Nazi Germany. She also used her money to help set up a school to train psychoanalysts in Paris. She made a lifelong study of female sexuality that produced several books, including Feminine Sexuality (1953). She admired the writings of Edgar Allan Poe and wrote The Life and Works of Edgar Allan Poe: A Psychoanalytic Interpretation (1949).
Sie war die Urenkelin Lucien Bonapartes, des Bruders von Napoléon Bonaparte. 1907 heiratete sie Prinz Georg von Griechenland. Sie übersetzte die Werke Freuds. Sie verfasste Studien über Edgar Allan Poe, die Triebtheorie und die weibliche Sexualität. land.