The Telegraph said of her: "Brigid Brophy was an outspoken campaigner on issues as diverse as humanism, animal rights, feminism, pornography, homosexual rights, the Vietnam War and religious education in schools (she disapproved of only the last two)." She was 25 when her first book of short stories, The Crown Princess, was published; it was followed in the same year by her novel, Hackenfeller's Ape.
In 1954, she married Michael Levey, an art historian who became director of the British National Gallery and was knighted in 1981. The couple had one daughter. She wrote further novels, several non-fiction books and essays. She wrote about her struggle with multiple sclerosis in her book, Baroque 'n' Role (1987).