Setske de Haan was born on 24 November 1889 in the village Oranjewoud in the province Friesland in the Netherlands. She was the daughter of IJnze de Haan, a headmaster and history teacher, and Froukje de Groot.
In 1914, she met Leo Beek, a department store manager as well as a reserve infantry officer. They married on 2 February 1916 and had two sons, Leo and IJnze. Her husband was arrested and later executed in the Westerbork transit camp in 1944, though it was 1946 before she learned of his fate. She died on 31 October 1948 in Bussum, Netherlands