Evelyn Pickering was born in London to a privileged, upper-class British family, and educated at home. She started art lessons as a teenager. She attended the South Kensington National Art Training School and the Slade School of Art from 1873 to 1876. Despite the disapproval of her parents for her chosen career as an artist, she enjoyed the support her uncle, the Pre-Raphaelite painter John Roddam Spencer Stanhope. In 1876, she had her first exhibition of a painting at the Dudley Gallery. In the early 1880s, she moved her studio out of her family home to the popular Trafalgar Studios in Chelsea. She made periodic trips to Italy to study the Old Masters, and also was active in London literary and artistic circles that included Violet Paget (Vernon Lee), Emily Susan Ford, and Margaret Burne-Jones. In 1887, she married William De Morgan, a ceramic designer from a bohemian, intellectual family. Their mutual interests included social reform, spiritualism, and music. They made frequent trips to Italy together and visited Spencer Stanhope at his villa near Florence. Evelyn De Morgan produced about 100 oil paintings and more than 300 drawings during her career. Her works often featured strong Biblical and classical women and early Christian saints, especially virgin martyrs. Some art critics call her a late Pre-Raphaelite, while others consider her a Symbolist. In 1909, the De Morgans published their spiritualist writings anonymously as The Result of An Experiment. In 1916, during World War I, Mrs. De Morgan's last exhibition was held as a benefit for the British and Italian Red Cross.