Natasha Trethewey was born in Gulfport, Mississippi, in 1966. She earned an M.A. in poetry from Hollins University and M.F.A. in poetry from the University of Massachusetts.
Her first collection of poetry, Domestic Work (2000), was selected by Rita Dove as the winner of the inaugural Cave Canem Poetry Prize for the best first book by an African American poet and won both the 2001 Mississippi Institute of Arts and Letters Book Prize and the 2001 Lillian Smith Award for Poetry.
Since then, she has published two more collections of poetry, including Native Guard (Houghton Mifflin, 2006), which received the Pulitzer Prize for Poetry, and Bellocq's Ophelia (2002). Her work has appeared in Agni, The American Poetry Review, The Best American Poetry, Callaloo, Gettysburg Review, The Massachusetts Review, New England Review, North American Review, and The Southern Review, among other magazines and anthologies.