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Immune Biology of Allogeneic Hematopoietic…
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Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation:…

by Gérard Socié

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Amazon.com Product Description (ISBN 0124160042, Hardcover)

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia (GVL) effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future.

Allogeneic HSCT is a medical procedure in which a patient receives blood-forming stem cells from a genetically similar but not identical donor. This procedure is commonly performed for people with diseases of the blood, bone marrow, or certain cancers, but it remains risky with many possible complications. As such, experimental practice is reserved for preclinical animal models including the mouse and dog.

These animal models have been essential in developing transplant protocols, including preclinical testing of conditioning regimens, treatment of GVHD, and understanding the pathology of GVHD as well as the immunological mechanisms of GVHD and GVL effect. However, recent research has revealed significant species differences between humans and animal models that must be considered when relating animal model studies to clinical allogeneic HSCT scenarios.

Brings together perspectives leading laboratories and clinical research groups to highlight advances from bench to the bedsideGuides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic HSCT scenariosCategorizes the published advances in various aspects of immune biology of allegeneic HSCT to illustrate opportunities for clinical applications

(retrieved from Amazon Thu, 12 Mar 2015 18:03:46 -0400)

Providing accurate, at-a-glance information on managing the diseases of birds and exotic pets, Clinical Veterinary Advisor: Birds and Exotic Pets is the only comprehensive resource on the market covering birds, reptiles, small mammals, and other non-traditional pets. Concise summaries of hundreds of common medical problems help you consider differential diagnoses, recommend diagnostic tests, interpret results mindful of unique species differences, utilize important concepts of species-specific husbandry and nutrition, prescribe treatments, and provide follow-up care. With contributions from recognized avian and exotics experts and edited by Jrg Mayer and Thomas M. Donnelly, this clinical reference provides all the information you need in one book! Six-books-in-one format includes six separate sections: Diseases and Disorders, Procedures and Techniques, Differential Diagnosis, Laboratory Tests, Clinical Algorithms, and Zoonoses. In-depth, cutting-edge coverage includes all exotic species - birds, reptiles, pocket pets, amphibians, and fish - in one comprehensive resource. Concise summaries feature a definition of each problem, epidemiology, physical findings and clinical presentation, etiology, differential diagnosis, diagnostic workup (such as laboratory tests and imaging studies), treatment, prognosis and patient follow-up, zoonotic potential, and references. Diagnostic and treatment algorithms provide easy-to-follow, step-by-step guidance to clinical assessment and treatment planning. A companion website includes the complete text from the book, making the entire contents fully searchable, along with 250 full-color illustrations, client handouts, and the ability to print out any pages.… (more)

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