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Clinical trial design challenges in mood…
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Clinical trial design challenges in mood disorders

by Mauricio Tohen

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Amazon.com Product Description (ISBN 0124051707, Hardcover)

Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders.  Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results.  Traditional trial designs are included as well as novel analytic techniques.  The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice.  With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients.

Summarizes common trial design problems and their solutionsEncompasses funding, subject selection, regulatory issues and moreIdentifies best practices for definitive and generalizable resultsIncludes traditional trial designs and novel analytic techniques Represents academia, industry, regulatory agencies, and advocacy groups

(retrieved from Amazon Mon, 13 Jul 2015 11:14:28 -0400)

Poor clinical trial designs result in failed studies wasting hundreds of thousands of dollars in research funds. Poor clinical trial designs limit the rapid advancement of cures for disorders. Yet it's relatively easy to avoid classic poor designs via education about what constitutes good design and what the potential outcomes are for any shortcuts taken. The proposed book outlines the classic problems that researchers are faced with in designing clinical trials, whether its money, selection of subjects, regulatory issues etc, and how best to address them for the most definitive and generalizable results. This book is specific to clinical trial issues in psychiatric research, and comes from a task force in Bipolar Research. The contents herein were identified as the most major issues in psychiatric research. Authored by international contributors from academia, industry, regulatory agencies, and advocacy groups, this book summarizes problems in clinical design and the results of same, and whether and how the results can be applied into clinical practice.… (more)

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