In the Patron Saint of Liars, Rose is a young wife of three years who concludes she married by mistake, that she misinterpreted teenage lust as a sign from God. Newly pregnant and uanble to continue a life with a man she doesn't love, Rose decides to leave. She abandons her quiet, inoffensive husband and their life at the Southern California seaside of the 1960's. Most of the odd and troubled characters fascinate and confound us. In the end, Rose surprises us on more time, and Sissy grows up, showing herself neither a liar nor a "leaver."