Shlomo Breznitz was born in to a Jewish family in Bratislava, Czechoslovakia (present-day Slovakia). During World War II, his parents were deported to Auschwitz, but managed to place him and his 10-year-old sister in hiding in a Roman Catholic orphanage. His father was killed at Auschwitz, but his mother survived, and they emigrated to Israel in 1949. In 1965, at the Hebrew University of Jerusalem, he became the first person to receive a Ph.D. degree in the new field of psychology in Israel.
From 1969 until 1971, he served as a consultant to the Israeli Air Force on problems of stress. He then joined the faculty of Haifa University and rose to become a full professor and then president of that university. In 1979, he was the founding director of the Ray D. Wolfe Center for Study of Psychological Stress there. Dr. Breznitz also has been a visiting professor at the London School of Economics, University of California-Berkeley, Stanford, the National Institutes of Health and Rockefeller University, and a visiting scientist at the National Institute of Mental Health. In addition to scholarly articles and research reports, he has written several books and has contributed chapters to more than 20 other books. In 1999 he retired from Haifa University and founded Cognifit, a brain fitness software company. He was elected to the Israeli Knesset in 2006 and served one year. His memoir of his childhood, Memory Fields, was published in English in 1992.