Opstand in Sobibor deals with the present-day life of four people who, together with four hundred other people, took part in the famous revolt in Sobibor in 1943. Van den Bergh: "The most intense moment of survival for the people in the film was the escape from Sobibor. But after that, life continued for them. They haved not stopped surviving. Therefore, I wanted to show that the drama stops and that reconciliation is possible. (fonte: Idfa.nl)

Attraverso interviste e documenti, in primis le parole del sopravvissuto alla rivolta di Sobibor Shlomo Szmainzer, e immagini del caso del criminale nazista Gustav Wagner, il comandante di Sobibor rintracciato in Brasile, viene ricostruita la storia del centro di sterminio.