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Codon evolution mechanisms and models

by Gina Cannarozzi

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Codon-based models of evolution are a relatively new addition to the toolkit of. computational biologists, and in recent years remarkable progress has been made in. this area. The study of evolution at the codon level captures information contained. in both amino acid and synonymous DNA substitutions. By combining these two types of. information, codon analyses are more powerful than those of either amino acid or DNA. evolution alone. This is a clear benefit for most evolutionaryanalyses, including. phylogenetic reconstruction, detection of selection, ancestral sequence. reconstruction, and al… (more)

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Codon-based models of evolution are a relatively new addition to the toolkit of. computational biologists, and in recent years remarkable progress has been made in. this area. The study of evolution at the codon level captures information contained. in both amino acid and synonymous DNA substitutions. By combining these two types of. information, codon analyses are more powerful than those of either amino acid or DNA. evolution alone. This is a clear benefit for most evolutionaryanalyses, including. phylogenetic reconstruction, detection of selection, ancestral sequence. reconstruction, and al

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