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Topics in Fluorescence Spectroscopy, Advanced Concepts in Fluorescence Sensing Part B: Macromolecular Sensing, is the tenth volume in the popular series Topics in Fluorescence Spectroscopy, edited by Drs. Chris D. Geddes and Joseph R. Lakowicz. This volume incorporates authoritative macromolecular analytical fluorescence sensing reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of fluorescence. This volume directly compliments Volume 9 in the series, Part A: Small Molecule Sensing. Advanced Concepts in Fluorescence Sensing Part B: Macromolecular Sensing is an essential reference for any lab working in the analytical fluorescence sensing field. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of macromolecular fluorescence sensing will find it an invaluable resource. Topics in Fluorescence Spectroscopy, Advanced Concepts in Fluorescence Sensing Part B: Macromolecular Sensing topics include: Protein-based Biosensors with Polarization based Transduction GFP Sensors Fluorescent Saccharide Sensors Fluorescent Pebble Nano-Sensors Aptamers for Macromolecular Sensing Molecular Imprinting Excimer Sensing About the Editors: Chris D. Geddes is an Associate Professor of Fluorescence Spectroscopy, Director of the Institute of Fluorescence, and Associate Director of the Center for Fluorescence Spectroscopy at the University of Maryland Biotechnology Institute, Medical Biotechnology Center, Baltimore. He is the Editor-in-Chief of the Journal of Fluorescence and both the Editor-in-Chief and Founding Editor of the Who's Who in Fluorescence and Reviews in Fluorescence annual volumes, as well as Executive Director of the Society of Fluorescence. Dr Geddes has published over 100 scientific articles, papers, review articles, books and book chapters on the principles and applications of fluorescence. Joseph R. Lakowicz is Professor of Biochemistry at the University of Maryland School of Medicine, Baltimore, and Director of the Center for Fluorescence Spectroscopy. Dr. Lakowicz has published over 400 scientific articles, has edited numerous books, holds 16 issued patents, and is the author of the widely used text, Principles of Fluorescence Spectroscopy.