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This new text combines highly readable pharmacology content with clinically oriented nursing to focus on the nurse's role of administering drugs, monitoring their effects, and patient education. A strong presentation of pathophysiology and pharmacology, it includes three distinct sections: pathophysiology, drug class, and application to practice. Emphasizes the pathophysiologic basis for understanding the mechanisms of drug action. Presents comprehensive nursing implications in separate Application to Practice sections with headings and icons for Lifespan Considerations, Cultural/Social Considerations, Goals for Therapy, and Case Studies. Highlights prototype drugs in drug class listing. Includes content on Pharmacoeconomics & Evidence-Based Practice and Over-the-Counter Drugs & Herbal Remedies to provide a focus on contemporary topics. Presents pharmacology in a consistent format with headings for mechanisms of action, uses, pharmacokinetics and pharmacodynamics, adverse reactions and contraindications, toxicity, and interactions. Includes nursing implications with coverage of assessment, goals of therapy, interventions, and evaluation. Features special boxes with icons for Herbal Interactions, Dietary Considerations, Evidence-Based Practice and Drug Abuse Alerts. Features lifespan content in separate chapters on perinatal, pediatric, and geriatric pharmacotherapeutics. Presents real-life Case Studies focusing on the nurse's role in administering drugs, monitoring their effects, and patient education, followed by the Patient History and Critical Thinking Questions and Answers. Includes Drug History-Taking Questions in both Spanish and English on a tear-out card. Provides key terms and page reference in chapter openers; terms are printed in color in the narrative. Identifies Canadian trade names with a maple leaf icon. Provides stable Internet Resources at the end of chapters. Includes Patient Problem boxes in several drug chapters accompanied by solutions. Provides a Disorders Index for easy reference along with a standard index. Features a colorful design for visual appeal.