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This case study documents the experience of the Pan Caribbean Partnership Against AIDS (PANCAP) to mobilize the response to AIDS in the region. It highlights both the Partnership's successes as well as the challenges it continues to face in supporting effective action on AIDS in all of its 29 countries. Divided into 12 chapters, which cover some of the following areas, including: the background to the AIDS crises; the regional response, and how PANCAP has managed such a response, along with projections of what PANCAP needs to accomplish in the future.