Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine

by William Rosen

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As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and show more eccentric characters. He explains why, given the complex nature of bacteria--and their ability to rapidly evolve into new forms--the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative--a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity's relationship with nature since the invention of agriculture ten thousand years ago. show less

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Academic Scientists and the Pharmaceutical Industry. Swann (1) Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicine. Stephens et al (1) Development and Production of Synthetic Gasoline. Roth (1) Discovering: Inventing and Solving Problems at the Frontiers of Scientific Knowledge. Root-Bernstein (1) Effect of BCG Vaccination Against Mycobacterium tuberculosis Infection in Children: Systematic Review and Meta-analysis. Roy et al. British Medical Journal. 2014 (1) Ehrlich; Bertheim; and Atoxyl: The Origins of Modern Chemotherapy. Riethmiller. Bulletin of the History of Chemistry. 1999 (1) Executive Order 8;807: Establishing the Office of Scientific Research and Development. 1941 (1) FDA and the Practice of Pharmacy: Prescription Drug Regulation Before the Durham-Humphrey Amendment of 1951. Swann. Pharmacy in History. 1994 (1) How Scientists Really Think. Root-Bernstein. Perspectives in Biology and Medicine. 1987 (1) Immigrant Entrepreneurship: German American Business Biographies; 1720 to the Present. Stevenson (1) John F. Fulton; Coccidioidomycosis; and Penicillin. Tager. Yale Journal of Biology and Medicine. 1976 (1) Legends of Literature: The Best Articles; Interviews; and Essays from the Archives of Writer's Digest Magazine. Sexton (1) Living in the Shadow of Death: Tuberculosis and the Social Experience of Illness in American History. Rothman (1) Louis Pasteur and the Hidden World of Microbes. Robbins (1) Max Tischler; 1906-1989: A Biographical Memoir. Sarrett (1) Mycobacterium tuberculosis Pathogenesis and Molecular Determinants of Virulence. Smith. Clinical Microbiology Reviews. 2003 (1) Overview of Benzene-Induced Aplastic Anaemia. Smith. European Journal of Haemotology: Supplementum. 1996 (1) Pills; Profits; and Politics. Silverman et al (1) Production of Penicillin in the United States (1941-1946). Richards. Nature. 1964 (1) Production of Penicillin. Silcox. Chemical Engineering News. 1946 (1) Taking Your Medicine: Drug Regulation in the United States. Temin (1) The American Synthetic Organic Chemicals Industry: War and Politics; 1910-1930. Steen (1) The Concept of Disease: Structure and Change. Thagard (1) The Legend of Pfizer. Rodengen (1) The Most Powerful Idea in the World: A Story of Steam; Industry; and Invention. Rosen (1) The Pursuit of Perfection: The Promise and Perils of Medical Enhancement. Rothman (1) The Therapeutic Revolution: Medicine; Meaning; and Social Change in Nineteenth Century America. Rosenberg. Perspectives in Biology and Medicine. 1977 (1) The True Story of the Discovery of Streptomycin. Schatz. Actinomycetes. 1993 (1) The Youngest Science: Notes of a Medicine Watcher. Thomas (1) Venereal Disease in Literature. Rolleston. British Journal of Venereal Disease. 1934 (1)

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2 reviews
http://www.audiofilemagazine.com/reviews/read/127948/

Narrator Rob Shapiro’s resonant baritone carries the listener smoothly through this fascinating history of the chemicals and the personalities that helped create contemporary medical culture.
½
Topic sounds interesting.

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Genres
Nonfiction, Science & Nature, General Nonfiction, History
DDC/MDS
615.7TechnologyMedicine & healthPharmacology and therapeuticsMedicines grouped by effects
LCC
RM409 .R67MedicineTherapeutics. PharmacologyTherapeutics. PharmacologyDrugs and their actions
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