Acceptable Risk
by Robin Cook
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HTML:Robin Cook has always been on the cutting edge of the latest medical controversies. In Acceptable Risk, he confronts one of the most provocative issues of our time: personality-altering drugs and the complex moral questions they raise. Neuroscientist Edward Armstrong has managed to isolate a psychotropic drug with a strange and dark history—one that may account for the public hysteria during the Salem witch trials. In a brilliant designer-drug transformation, it is developed into an show more antidepressant with truly startling therapeutic capabilities. But who can be sure the drug is safe for consumers? Who defines the boundaries of "normal" human behavior? And if the drug's side effects are proven to be dangerous—even terrifying—how far will the medical community go to alter their standards of...Acceptable Risk. Literature. Thriller. Fiction. Mystery. show lessTags
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So strange to read this now when there are so many potential and yes, horrible, changes for women coming with the banning of abortion decision coming down soon. When this book was written, 1994, the main character....Kim....was comparing her freedoms as a woman to those of her ancestor's back in the late1600s. Really incredible to read this right NOW. I have read and loved all of the books that I've read by Robin Cook. I hope he is writing a book about the current situation facing women as we seem to be going backwards in time! I found this story fascinating--he is so good at making his characters live, moving with enough detail so that you can picture what jeu are doing in your mind.
“Acceptable Risk” is part historical mystery and part medical thriller. It is about Kim, a woman who explores her own identity by researching the mystery of her ancestor Elizabeth’s alleged execution as a witch. Meanwhile, her boyfriend Edward succumbs to the financial allure of high-profile drug development. His research proceeds with supernatural velocity, propelling him and his research team into unethical, and tragic, methods. As a fellow medical scientist, I found the description of drug development a little unsettling and unreal. His eerie successes and failures parallel the dark supernaturalness of the Salem witchcraft trials. In this book, Cook questions the ethics behind development of million-dollar drugs and the safety show more of casual use of psychoactive drugs. Although the plot was not as fast-paced or eerily believable as some of Cook’s other books, the historical mystery was a refreshing change from main-stream medical thrillers. show less
This is the first Robin Cook's books that I have ever read.
Usually I'm not into Medical thrillers, however, this one was recommended to me because of my interest in the Salem Witch trials.
I really enjoyed the book. It was a quick read and kept me guessing what was going to happen next.
Usually I'm not into Medical thrillers, however, this one was recommended to me because of my interest in the Salem Witch trials.
I really enjoyed the book. It was a quick read and kept me guessing what was going to happen next.
So I read this story for the first time as a teenager and actually read it during the winter months in Pennsylvania. I loved the atmosphere of this book and it started my interest in the Salem Witch Trials as well. It was great to re-read my copy again and besides a few pacing issues here and there, I thought this was a solid thriller to read for Halloween Bingo 2019. I won't lie though that the medical mystery that Cook gets into is a reach although his proposed solutions to what afflicted the girls during the Salem Witch Trials was also brought up via Shirley Jackson when she wrote "The Witchcraft of Salem Village." I don't think that the "theory" is true at all and I kind of just hard shrugged my shoulders at it. I consider this more show more science fiction than anything and thought this book reminded me a lot of some of Dean Koontz's earlier works.
"Acceptable Risk" starts off with a flashback to the Salem Witch Trials and the soon to be hanging of a woman, Elizabeth Stewart, is accused of being a witch.We don't know what evidence the man holding the proceedings is talking about, but Elizabeth is accused of also afflicting children as well. Then the book proceeds to the "present" day with one of Elizabeth's descendants, Kimberly Stewart. Kimberly is a nurse and lives in Cambridge, Massachusetts. Kimberly is coming out of a relationship with a dickish resident (sorry he is) Kinnard when she gets set up with by her cousin with a medical researcher, Edward Armstrong. Kimberly and Edward hit it off and start dating. While dealing with that, she is trying to figure out what to do with her family's old home in Salem (where Elizabeth Stewart also lived) and while there, Edward finds a new strain of something that I can't even remember how to spell. Through his research, Edward finds that he can use this strain to turn it into a drug that has no negative side effects, but also causes the user to be more calm and confident.
Kimberly is shy and I felt for her. She is overwhelmed in a good way by Edward and quickly gets talked into things she is not sure about. I think that the biggest issue with Kimberly though is halfway through the book she just lets Edward and her cousin walk all over her. I also hard paused at her jumping into something so new with Edward right away and living with the guy. She also agrees to let the medical research company work out of her home and she is starting to have misgivings about the drug. She flounders around a lot and then starts talking to her ex who was the worst from the glimpse of him we get in the beginning of the book.
Edward is shy and him getting hooked on the wonder drug was a good look at how prescription drugs can cause people to become too dependent on them and the danger in taking them. His whole personality undergoes a change through the book.
We get some secondary characters, but mostly just have Kimberly and Edward's third person POVs. There's also a mystery going around about vandalism in the town of other things that Kimberly finds that get explained by the end of the book.
The writing I thought was good. Cook has Kimberly researching Elizabeth's history and the Salem Witch Trials with her trying to find out what evidence the town had to show that Elizabeth was a witch.
The flow though as I said at times gets a big bogged down whenever we get into the medical aspect of things with the new designer drug. I don't really get anything that Cook is getting into and thought that it seemed beyond strange that Edward and those he hired would just blithely take drugs that had not been through testing.
The setting of the old home that quickly gets overrun by Edward and his colleagues takes a dark turn after a while. Kimberly is having to deal with the fact that the home doesn't feel like hers and that many of the researchers are just haphazardly treating the home.
The ending felt gruesome to me and I have to say I wonder at how Cook left things since it seems as if this story would be perfect for a sequel. I also didn't like how things ended for Kimberly since I thought that Cook changed the whole tone of the book up and had to make it into a happily ever after for her. The "It was a dark and stormy night" piece from this book comes to the next to last scene with Kimberly running (from something) in the rain. show less
"Acceptable Risk" starts off with a flashback to the Salem Witch Trials and the soon to be hanging of a woman, Elizabeth Stewart, is accused of being a witch.We don't know what evidence the man holding the proceedings is talking about, but Elizabeth is accused of also afflicting children as well. Then the book proceeds to the "present" day with one of Elizabeth's descendants, Kimberly Stewart. Kimberly is a nurse and lives in Cambridge, Massachusetts. Kimberly is coming out of a relationship with a dickish resident (sorry he is) Kinnard when she gets set up with by her cousin with a medical researcher, Edward Armstrong. Kimberly and Edward hit it off and start dating. While dealing with that, she is trying to figure out what to do with her family's old home in Salem (where Elizabeth Stewart also lived) and while there, Edward finds a new strain of something that I can't even remember how to spell. Through his research, Edward finds that he can use this strain to turn it into a drug that has no negative side effects, but also causes the user to be more calm and confident.
Kimberly is shy and I felt for her. She is overwhelmed in a good way by Edward and quickly gets talked into things she is not sure about. I think that the biggest issue with Kimberly though is halfway through the book she just lets Edward and her cousin walk all over her. I also hard paused at her jumping into something so new with Edward right away and living with the guy. She also agrees to let the medical research company work out of her home and she is starting to have misgivings about the drug. She flounders around a lot and then starts talking to her ex who was the worst from the glimpse of him we get in the beginning of the book.
Edward is shy and him getting hooked on the wonder drug was a good look at how prescription drugs can cause people to become too dependent on them and the danger in taking them. His whole personality undergoes a change through the book.
We get some secondary characters, but mostly just have Kimberly and Edward's third person POVs. There's also a mystery going around about vandalism in the town of other things that Kimberly finds that get explained by the end of the book.
The writing I thought was good. Cook has Kimberly researching Elizabeth's history and the Salem Witch Trials with her trying to find out what evidence the town had to show that Elizabeth was a witch.
The flow though as I said at times gets a big bogged down whenever we get into the medical aspect of things with the new designer drug. I don't really get anything that Cook is getting into and thought that it seemed beyond strange that Edward and those he hired would just blithely take drugs that had not been through testing.
The setting of the old home that quickly gets overrun by Edward and his colleagues takes a dark turn after a while. Kimberly is having to deal with the fact that the home doesn't feel like hers and that many of the researchers are just haphazardly treating the home.
The ending felt gruesome to me and I have to say I wonder at how Cook left things since it seems as if this story would be perfect for a sequel. I also didn't like how things ended for Kimberly since I thought that Cook changed the whole tone of the book up and had to make it into a happily ever after for her. The "It was a dark and stormy night" piece from this book comes to the next to last scene with Kimberly running (from something) in the rain. show less
Oh, what horrors evolve from applying pure commercial profit to medical care. Beware the money men in lab coats. A story ahead of its time.
Acceptable Risk was quite a good book; it blends the Salem Witch Trials of the late 1600s together with events in the present where a scientist discovers a new drug produced by a fungus found in the basement of someone who was executed for witchcraft.
The scientist then has dreams of becoming rich by bringing a new miracle drug to market and in the rush to get it ready begins testing it on himself and his team, being a Robin Cook book it doesn't take much pondering to work out things don't go as planned.
I found the mixture of past and present enthralling and thought it really stimulated the imagination.
The scientist then has dreams of becoming rich by bringing a new miracle drug to market and in the rush to get it ready begins testing it on himself and his team, being a Robin Cook book it doesn't take much pondering to work out things don't go as planned.
I found the mixture of past and present enthralling and thought it really stimulated the imagination.
Review: Acceptable Risk by Robin Cook.
This book has many twist and turns. What a reader may think it’s a romance but soon turns out the reader is lead towards a medical quest and with traveling through a trip in history with an insight into a woman accused of witchcraft. The story brings the reader to the end in pure horror. This author has written many intriguing books that are hard to put down. There are some interesting questions lingering throughout the book, mainly the pros, cons and ethical implication of altering someone’s personality through drugs.
It’s about the Stewart family who live in Massachusetts and the story about their distant ancestors especially Elizabeth Stewart, whom through generations has been hidden in the show more past and told to never talk about the event or rumor about their persecuting of family members who were hung for practicing witchcraft in Salem in 1692. In the present Kimberly Stewart, a surgical nurse in Cambridge has decided to search for history about her family in a castle and land still there abandoned years ago and was left to her and her brother.
Than one day Kimberly found evidence that revealed in letters and files left in the castle over many years that the cause of the witch panic could be related to something other than the town of Salem knew. The story was very intriguing and plenty of events that kept the reader fascinated with great interest. show less
This book has many twist and turns. What a reader may think it’s a romance but soon turns out the reader is lead towards a medical quest and with traveling through a trip in history with an insight into a woman accused of witchcraft. The story brings the reader to the end in pure horror. This author has written many intriguing books that are hard to put down. There are some interesting questions lingering throughout the book, mainly the pros, cons and ethical implication of altering someone’s personality through drugs.
It’s about the Stewart family who live in Massachusetts and the story about their distant ancestors especially Elizabeth Stewart, whom through generations has been hidden in the show more past and told to never talk about the event or rumor about their persecuting of family members who were hung for practicing witchcraft in Salem in 1692. In the present Kimberly Stewart, a surgical nurse in Cambridge has decided to search for history about her family in a castle and land still there abandoned years ago and was left to her and her brother.
Than one day Kimberly found evidence that revealed in letters and files left in the castle over many years that the cause of the witch panic could be related to something other than the town of Salem knew. The story was very intriguing and plenty of events that kept the reader fascinated with great interest. show less
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Author Information

72+ Works 43,241 Members
Robin (Robert William Arthur) Cook, the master of the medical thriller novel, was born to Edgar Lee Cook, a commercial artist and businessman, and Audrey (Koons) Cook on May 4, 1940, in New York City. Cook spent his childhood in Leonia, New Jersey, and decided to become a doctor after seeing a football injury at his high school. He earned a B.A. show more from Wesleyan University in 1962, his M.D. from Columbia University in 1966, and completed postgraduate training at Harvard before joining the U.S. Navy. Cook began his first novel, The Year of the Intern, while serving on a submarine, basing it on his experiences as a surgical resident. In 1979, Cook wed Barbara Ellen Mougin, on whom the character Denise Sanger in Brain is based. When Year of the Intern did not do particularly well, Cook began an extensive study of other books in the genre to see what made a bestseller. He decided to focus on suspenseful medical mysteries, mixing intricately plotted murder and intrigue with medical technology, as a way to bring controversial ethical and social issues affecting the medical profession to the attention of the general public. His subjects include organ transplants, genetic engineering, experimentation with fetal tissue, cancer research and treatment, and deadly viruses. Cook put this format to work very successfully in his next books, Coma and Sphinx, which not only became bestsellers, but were eventually adapted for film. Three others, Terminal, Mortal Fear, and Virus, and Cook's first science- fiction work, Invasion, have been television movies. In 2014 her title, Cell made The New York Times Best Seller List. (Bowker Author Biography) show less
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Reader's Digest: Acceptable Risk | Hidden Riches | The Land God Gave to Cain | Voices of Summer by Reader's Digest
Reader's Digest Condensed Books: Acceptable Risk • Heart of the Dreaming • Eye of the Storm • This Child is Mine by Reader's Digest
Common Knowledge
- Canonical title
- Acceptable Risk
- Original title
- Acceptable risk
- Original publication date
- 1994
- People/Characters
- Edward Armstrong; Kimberly Stewart; Stanton Lewis
- Related movies
- Acceptable Risk (2001 | IMDb)
- Epigraph
- the Devil hath power
to assume a pleasing shape.
Hamlet
William Shakespeare - Dedication
- For Jean
"The guiding light" - First words
- Spurred on by the penetrating cold, Mercy Griggs snapped her riding crop above the back of her mare.
- Last words
- (Click to show. Warning: May contain spoilers.)It was the only way she could imagine to repay Elizabeth for the understanding she'd provided.
- Original language*
- Inglés
*Some information comes from Common Knowledge in other languages. Click "Edit" for more information.
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